When this balance is lost in and around the cell, so is production within the cell. Overall production suffers and the animal or bird continues to decline until homeostasis is restored.
Chemical reaction doubled
An increase in temperature of 100C (500F) will double the rate of chemical reactions. pH influences enzyme activity.
Most enzymes function best when conditions are near neutrality(pH 6.5 - 7.5).
Any enzyme reaction is likely to be only one simple link in a long sequence of reactions (a metabolic pathway) that are necessary for activity and survival of the cell.
Many diets have primary deficiencies or toxicities. Not all minerals are absorbed with equal efficiency and therefore, what is available to the animal will not necessarily be the same as that shown as present in the feed analysis.